[Eclipsemullet]

In that configuration you would want to set GPSNavX or MacENC this way

GPS panel Settings drawer - Port: /dev/cu.KeySerial1, Rate: 38400, Type: Other

AIS panel Settings drawer - Check "Use GPS Port", otherwise you will get the error port cannot be opened because the GPS panel is all ready using that port.

Thanks. I will give the settings you suggest a go.